The SLC22A3 Polyclonal Antibody (CAB18588) is a valuable tool for researchers studying SLC22A3, a member of the SLC22A transporter family involved in the cellular uptake of organic ions. This antibody, raised in rabbits, has high specificity and sensitivity for human samples, making it ideal for use in Western blot applications. By binding to the SLC22A3 protein, this antibody allows for accurate detection and analysis in various cell types, facilitating research in the fields of pharmacology, toxicology, and drug development.
SLC22A3 plays a crucial role in drug transport and disposition in the body, impacting the efficacy and toxicity of a wide range of medications. Understanding the function and regulation of SLC22A3 is essential for improving drug therapies and predicting drug-drug interactions. This antibody provides researchers with a reliable tool for investigating the role of SLC22A3 in drug transport, metabolism, and drug-drug interactions, ultimately advancing research in personalized medicine and precision pharmacology.
Product Name:
SLC22A3/OCT3 Rabbit Polyclonal Antibody
SKU:
CAB18588
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 289-349 of human SLC22A3/OCT3 (NP_068812.1).
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein.
Purification Method:
Affinity purification
Gene ID:
6581
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse liver, using SLC22A3/OCT3 Rabbit pAb (CAB18588) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
