The SLC22A24 Polyclonal Antibody (PACO39646) is a highly specific tool for researchers studying SLC22A24, a member of the solute carrier family involved in the transport of organic cations. This antibody, generated in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blotting applications. By targeting the SLC22A24 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in the fields of pharmacology, toxicology, and drug metabolism.
SLC22A24 is a vital transporter protein involved in the uptake and excretion of endogenous substances and drugs, playing a crucial role in drug pharmacokinetics and drug-drug interactions. Its function in cellular transport processes makes it a valuable target for research into drug metabolism, personalized medicine, and drug discovery. Understanding the role of SLC22A24 is essential for developing novel therapeutic strategies and optimizing drug treatments for various diseases and conditions.
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO39646 at dilution of 1:100.
Immunofluorescent analysis of 293T cells using PACO39646 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
integral component of plasma membrane, inorganic anion exchanger activity, sodium-independent organic anion transmembrane transporter activity, anion transmembrane transport, sodium-independent organic anion transport
Synonyms:
Solute carrier family 22 member 24, SLC22A24
UniProt Protein Function:
Subcellular location: Membrane; Multi-pass membrane protein Potential. Sequence similarities: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. [View classification]
UniProt Protein Details:
NCBI Summary:
SLC22A24 belongs to a large family of transmembrane proteins that function as uniporters, symporters, and antiporters to transport organic ions across cell membranes (Jacobsson et al., 2007 [PubMed 17714910]).[supplied by OMIM, Mar 2008]
