The SLC22A10 Polyclonal Antibody (PACO64523) is a valuable tool for researchers studying SLC22A10, a transporter protein involved in the transport of organic cations. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.SLC22A10, also known as Octn2, plays a crucial role in the uptake and efflux of various organic cations, including drugs and toxins, across cell membranes. Its function in regulating the concentration of these compounds in cells makes it an important target for studies in pharmacology, toxicology, and drug development.
By enabling the detection and analysis of SLC22A10 in different cell types, this antibody is ideal for investigating the role of this transporter protein in various physiological and pathological processes. Researchers can use this antibody to better understand the mechanisms underlying drug transport and metabolism, as well as potential implications for therapeutic interventions in conditions such as renal dysfunction and drug interactions.
Antibody Name:
SLC22A10 Antibody (PACO64523)
Antibody SKU:
PACO64523
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
IF:1:100-1:500
Species Reactivity:
Human
Immunogen:
Recombinant Human Solute carrier family 22 member 10 protein (37-145AA)
Immunofluorescence staining of SH-SY5Y cells with PACO64523 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
integral component of plasma membrane, inorganic anion exchanger activity, sodium-independent organic anion transmembrane transporter activity, urate transmembrane transporter activity, sodium-independent organic anion transport, urate transport
Synonyms:
Solute carrier family 22 member 10 (Organic anion transporter 5), SLC22A10, OAT5
