The SLC20A2 Polyclonal Antibody (CAB6739) is specifically designed for research involving SLC20A2, a key protein involved in phosphate transport and homeostasis in the body. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the SLC20A2 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential tool for studies in molecular biology and metabolic disorders.SLC20A2, also known as the phosphate transporter PiT-2, plays a crucial role in maintaining phosphate balance in the body by facilitating the transport of inorganic phosphate across cell membranes.
Dysregulation of SLC20A2 has been implicated in various metabolic disorders, including familial idiopathic basal ganglia calcification (FIBGC), underscoring its importance in human health. By studying the function and regulation of SLC20A2, researchers can gain valuable insights into the pathogenesis of these diseases and potentially identify new therapeutic targets for treatment.
Product Name:
SLC20A2 Rabbit Polyclonal Antibody
SKU:
CAB6739
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 235-485 of human SLC20A2 (NP_001244110.1).
This gene encodes a member of the inorganic phosphate transporter family. The encoded protein is a type 3 sodium-dependent phosphate symporter that plays an important role in phosphate homeostasis by mediating cellular phosphate uptake. The encoded protein also confers susceptibility to viral infection as a gamma-retroviral receptor. Mutations in this gene may play a role in familial idiopathic basal ganglia calcification. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
6575
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC20A2 Rabbit pAb (CAB6739) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
