The SLC1A6 Polyclonal Antibody (CAB2904) is a valuable tool for research involving the SLC1A6 protein, a key player in amino acid transport and neurotransmitter regulation. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it ideal for use in Western blot applications.SLC1A6, also known as excitatory amino acid transporter 4 (EAAT4), is crucial for maintaining proper excitatory neurotransmission by facilitating the uptake of glutamate in the brain. Dysregulation of SLC1A6 has been implicated in various neurological disorders, including epilepsy, Alzheimer's disease, and schizophrenia.
Therefore, studying the expression and function of SLC1A6 is essential for unraveling the mechanisms underlying these conditions and identifying potential therapeutic targets.With its ability to detect and analyze SLC1A6 in diverse cell types, the CAB2904 antibody is a valuable asset for researchers in neuroscience, pharmacology, and neurology. By uncovering the role of SLC1A6 in brain function and pathology, this antibody contributes to advancing our understanding of neurological diseases and developing novel treatment strategies.
Product Name:
SLC1A6 Rabbit Polyclonal Antibody
SKU:
CAB2904
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 155-265 of human SLC1A6 (NP_001259016.1).
Predicted to enable high-affinity glutamate transmembrane transporter activity. Involved in neurotransmitter uptake. Located in intermediate filament cytoskeleton and plasma membrane.
Purification Method:
Affinity purification
Gene ID:
6511
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SLC1A6 antibody (CAB2904) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
