The SLC1A5 Polyclonal Antibody (CAB6981) is specifically designed for research involving SLC1A5, a cell surface transporter protein that plays a crucial role in amino acid metabolism and cell growth. This antibody, raised in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding to the SLC1A5 protein, researchers can effectively detect and analyze its expression in various cell types, making it an excellent tool for studies in metabolism, cancer biology, and cell proliferation.SLC1A5, also known as neutral amino acid transporter ASCT2, is essential for the uptake of glutamine, a vital amino acid for cellular processes such as protein synthesis and cell signaling.
Dysregulation of SLC1A5 has been implicated in various diseases, including cancer, where increased expression of this transporter is associated with accelerated tumor growth and metastasis. Understanding the function and regulation of SLC1A5 is crucial for developing targeted therapies that exploit its role in cancer metabolism.Overall, the SLC1A5 Polyclonal Antibody provides researchers with a valuable tool for investigating the biological functions of SLC1A5 and its implications in disease pathology, offering insights that may lead to the development of novel therapeutic strategies for conditions where SLC1A5 dysregulation plays a key role.
Product Name:
SLC1A5 Rabbit Polyclonal Antibody
SKU:
CAB6981
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 154-224 of human SLC1A5 (NP_005619.1).
The SLC1A5 gene encodes a sodium-dependent neutral amino acid transporter that can act as a receptor for RD114/type D retrovirus (Larriba et al., 2001 [PubMed 11781704]).
Purification Method:
Affinity purification
Gene ID:
6510
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC1A5 Rabbit pAb (CAB6981) at 1:700 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime: 30s.
