The SLC1A4 Polyclonal Antibody (CAB12507) is a valuable tool for researchers studying SLC1A4, a key transporter involved in the regulation of neurotransmitter glutamate. This antibody, generated in rabbits, exhibits high specificity and reactivity towards human samples, making it suitable for use in Western blot applications. By selectively binding to the SLC1A4 protein, this antibody facilitates the detection and analysis of SLC1A4 expression in various cell types.SLC1A4, also known as alanine-serine-cysteine transporter 1 (ASCT1), plays a crucial role in the uptake of glutamate, an essential neurotransmitter in the central nervous system. Dysregulation of SLC1A4 has been implicated in various neurological disorders, including epilepsy and neurodegenerative diseases.
As such, understanding the function and expression of SLC1A4 is essential for unraveling the molecular mechanisms underlying these conditions and developing targeted therapies.Overall, the SLC1A4 Polyclonal Antibody (CAB12507) is a reliable reagent for researchers investigating the role of SLC1A4 in neurological disorders and glutamate metabolism. Its specificity and versatility make it an essential tool for advancing our knowledge of this critical transporter and its potential implications in disease pathology.
Product Name:
SLC1A4 Rabbit Polyclonal Antibody
SKU:
CAB12507
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 140-220 of human SLC1A4 (NP_003029.2).
The protein encoded by this gene is a sodium-dependent neutral amino acid transporter for alanine, serine, cysteine, and threonine. Defects in this gene have been associated with developmental delay, microcephaly, and intellectual disability.
Purification Method:
Affinity purification
Gene ID:
6509
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SLC1A4 Rabbit pAb (CAB12507) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
