EAAT2/SLC1A2 Rabbit Polyclonal Antibody (CAB0910)
- SKU:
- CAB0910
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | EAAT2/SLC1A2 Rabbit Polyclonal Antibody |
SKU: | CAB0910 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 474-574 of human EAAT2/EAAT2/SLC1A2 (NP_004162.2). |
Sequence: | LDRM RTSV NVVG DSFG AGIV YHLS KSEL DTID SQHR VHED IEMT KTQS IYDD MKNH RESN SNQC VYAA HNSV IVDE CKVT LAAN GKSA DCSV EEEP WKRE K |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | GLT1; HBGT; DEE41; EAAT2; GLT-1; EIEE41; EAAT2/SLC1A2 |
Positive Sample: | Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Multi-pass membrane protein. |
Calculated MW: | 62kDa |
Observed MW: | 62kDa |
This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified.
Purification Method: | Affinity purification |
Gene ID: | 6506 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |