SLC1A1 Rabbit Polyclonal Antibody (CAB2903)
- SKU:
- CAB2903
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | SLC1A1 Rabbit Polyclonal Antibody |
SKU: | CAB2903 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 430-524 of human SLC1A1 (NP_004161.4). |
Sequence: | AEDV TLII AVDW LLDR FRTM VNVL GDAF GTGI VEKL SKKE LEQM DVSS EVNI VNPF ALES TILD NEDS DTKK SYVN GGFA VDKS DTIS FTQT SQF |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | DCBXA; EAAC1; EAAT3; SCZD18; hEAAC1; SLC1A1 |
Positive Sample: | Mouse lung,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Apical cell membrane, Cell membrane, Membrane, Multi-pass membrane protein. |
Calculated MW: | 57kDa |
Observed MW: | 70kDa |
This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect.
Purification Method: | Affinity purification |
Gene ID: | 6505 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |