The SLC18A3 Polyclonal Antibody (CAB16068) is a valuable tool for research involving the SLC18A3 protein, a member of the SLC18 transporter family responsible for vesicular storage and release of neurotransmitters. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the SLC18A3 protein, researchers can accurately detect and analyze this crucial transporter in a variety of cell types.SLC18A3 plays a crucial role in neurotransmitter storage and release, making it essential for proper neuronal function and communication. Dysregulation of SLC18A3 has been linked to various neurological disorders, including Parkinson's disease and schizophrenia, highlighting its importance in the field of neuroscience research.
By studying the function and regulation of SLC18A3, researchers can gain valuable insights into the mechanisms underlying these debilitating conditions and potentially identify novel therapeutic targets. Overall, the SLC18A3 Polyclonal Antibody is a reliable tool for investigating the role of SLC18A3 in neurotransmission and neurological disorders, offering researchers a valuable resource for advancing our understanding of brain function and exploring new avenues for therapeutic intervention.
Product Name:
SLC18A3 Rabbit Polyclonal Antibody
SKU:
CAB16068
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 473-532 of human SLC18A3 (NP_003046.2).
This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene.
Purification Method:
Affinity purification
Gene ID:
6572
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded rat brain using SLC18A3 Rabbit pAb (CAB16068) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
