The SLC17A6 Polyclonal Antibody (CAB15177) is a valuable tool for researchers studying the SLC17A6 protein, also known as VGLUT2. This protein is a vesicular glutamate transporter that plays a crucial role in neurotransmission by transporting glutamate into synaptic vesicles. The antibody, raised in rabbits, has high specificity and sensitivity for detecting SLC17A6 in human samples, making it perfect for use in Western blot applications.By targeting the SLC17A6 protein, researchers can investigate its role in synaptic transmission and neurotransmitter release in the central nervous system.
Understanding the function of SLC17A6 is essential for studying neurological disorders such as Parkinson's disease, Alzheimer's disease, and epilepsy, where disruptions in glutamate signaling are implicated. The SLC17A6 Polyclonal Antibody provides a valuable tool for elucidating the molecular mechanisms underlying these conditions and developing potential therapeutic interventions.
Product Name:
SLC17A6 Rabbit Polyclonal Antibody
SKU:
CAB15177
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 500-582 of human SLC17A6 (NP_065079.1).
Predicted to enable L-glutamate transmembrane transporter activity and neurotransmitter transmembrane transporter activity. Involved in neurotransmitter loading into synaptic vesicle. Predicted to be located in synaptic vesicle. Predicted to be active in excitatory synapse. Predicted to be integral component of synaptic vesicle membrane.
Purification Method:
Affinity purification
Gene ID:
57084
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SLC17A6 Polyclonal Antibody (CAB15177) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
