The SLC17A5 Polyclonal Antibody (CAB15425) is a valuable tool for research involving SLC17A5, a solute carrier protein involved in phosphate transport and metabolism. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the SLC17A5 protein, researchers can accurately detect and study this important transporter in various cell types, making it ideal for investigations in the fields of metabolism and renal function.
SLC17A5 is essential for the proper functioning of lysosomes and plays a critical role in the regulation of phosphate homeostasis. Dysregulation of SLC17A5 has been implicated in various metabolic disorders, such as X-linked hypophosphatemia and Dent disease. Understanding the mechanisms and pathways involving SLC17A5 is crucial for developing targeted therapies for these conditions, as well as expanding our knowledge of phosphate metabolism in health and disease.
Product Name:
SLC17A5 Rabbit Polyclonal Antibody
SKU:
CAB15425
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SLC17A5 (NP_036566.1).
This gene encodes a membrane transporter that exports free sialic acids that have been cleaved off of cell surface lipids and proteins from lysosomes. Mutations in this gene cause sialic acid storage diseases, including infantile sialic acid storage disorder and and Salla disease, an adult form.
Purification Method:
Affinity purification
Gene ID:
26503
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC17A5 Rabbit pAb (CAB15425) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
