The SLC16A9 Polyclonal Antibody (PAC020476) is a valuable tool for researchers studying the SLC16A9 protein, a member of the solute carrier family involved in transportation of monocarboxylates such as lactate and pyruvate. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the SLC16A9 protein, researchers can effectively detect and analyze its expression in various cell types, allowing for insightful investigations in the fields of metabolism and cancer research.SLC16A9, also known as the monocarboxylate transporter 9, plays a crucial role in the transport of monocarboxylates across cell membranes, impacting cellular metabolism and energy production.
Its involvement in lactate and pyruvate transport suggests its potential significance in cancer metabolism and tumor growth. Research on SLC16A9 can provide valuable insights into metabolic reprogramming in cancer cells and may offer new therapeutic strategies for targeting metabolic vulnerabilities in cancer treatment. Understanding the function of SLC16A9 is therefore essential for advancing our knowledge of metabolic pathways and their implications in disease progression.
Antibody Name:
SLC16A9 Antibody (PACO20476)
Antibody SKU:
PACO20476
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:5000, WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human SLC16A9
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Gel: 8%SDS-PAGE, Lysate: 60 µg, Lane 1-2: Human normal stomach tissue, Human stomach cancer tissue, Primary antibody: PACO20476(SLC16A9 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes.
Background:
MCT9 (monocarboxylate transporter 9), also known as SLC16A9 (solute carrier family 16, member 9 (monocarboxylic acid, transporter 9)) or C10orf36, is a 509 amino acid, multi-pass membrane protein that belongs to the major facilitator superfamily. Like other MCT proteins, MCT9 functions as a monocarboxylate transporter that catalyzes the rapid proton-linked transport of monocarboxylates across the plasma membrane.
Synonyms:
solute carrier family 16, member 9p
UniProt Protein Function:
Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane.
