Anti-SLC16A8 Antibody (PACO51954)

Antibody Name:	SLC16A8 Antibody (PACO51954)
Antibody SKU:	PACO51954
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC, IF
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200
Species Reactivity:	Human, Mouse
Immunogen:	Recombinant Human Monocarboxylate transporter 3 protein (432-504AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Western Blot. Positive WB detected in: K562 whole cell lysate, Jurkat whole cell lysate, HepG2 whole cell lysate, Mouse brain tissue. All lanes: SLC16A8 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 53 kDa. Observed band size: 53 kDa..
	Immunofluorescent analysis of A549 cells using PACO51954 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
	Immunohistochemistry of paraffin-embedded human eye tissue using PACO51954 at dilution of 1:100.

Background:	Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acid, derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).
Synonyms:	Monocarboxylate transporter 3 (MCT 3) (Solute carrier family 16 member 8), SLC16A8, MCT3

UniProt Protein Function:	SLC16A8: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
UniProt Protein Details:	Protein type:Transporter, SLC family; Transporter; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 22q12.3-q13.2 Cellular Component: membrane; plasma membrane Molecular Function:lactate transmembrane transporter activity; monocarboxylic acid transmembrane transporter activity Biological Process: lactate transport; leukocyte migration; pyruvate metabolic process
NCBI Summary:	SLC16A8 is a member of a family of proton-coupled monocarboxylate transporters that mediate lactate transport across cell membranes (Yoon et al., 1999 [PubMed 10493836]).[supplied by OMIM, Apr 2010]
UniProt Code:	O95907
NCBI GenInfo Identifier:	17433295
NCBI Gene ID:	23539
NCBI Accession:	O95907.1
UniProt Secondary Accession:	O95907,Q9UBE2,
UniProt Related Accession:	O95907
Molecular Weight:	52,319 Da
NCBI Full Name:	Monocarboxylate transporter 3
NCBI Synonym Full Names:	solute carrier family 16 member 8
NCBI Official Symbol:	SLC16A8
NCBI Official Synonym Symbols:	MCT3; REMP
NCBI Protein Information:	monocarboxylate transporter 3
UniProt Protein Name:	Monocarboxylate transporter 3
UniProt Synonym Protein Names:	Solute carrier family 16 member 8
Protein Family:	Monocarboxylate transporter
UniProt Gene Name:	SLC16A8
UniProt Entry Name:	MOT3_HUMAN

ELISA Kits

Human SLC16A8 ELISA Kit

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)