Anti-SLC16A8 Antibody (PACO20474)

Antibody Name:	SLC16A8 Antibody (PACO20474)
Antibody SKU:	PACO20474
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100
Species Reactivity:	Human
Immunogen:	Synthetic peptide of human SLC16A8

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane: Human fetal brain tissue, Primary antibody: PACO20474(SLC16A8 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes.
	The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO20474(SLC16A8 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).

Background:

SLC16A8 is a member of a family of proton-coupled monocarboxylate transporters that mediate lactate transport across cell membranes. Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acid, derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.

Synonyms:

solute carrier family 16 (monocarboxylate transporter), member 8

UniProt Protein Function:	SLC16A8: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
UniProt Protein Details:	Protein type:Transporter, SLC family; Transporter; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 22q12.3-q13.2 Cellular Component: membrane; plasma membrane Molecular Function:lactate transmembrane transporter activity; monocarboxylic acid transmembrane transporter activity Biological Process: lactate transport; leukocyte migration; pyruvate metabolic process
NCBI Summary:	SLC16A8 is a member of a family of proton-coupled monocarboxylate transporters that mediate lactate transport across cell membranes (Yoon et al., 1999 [PubMed 10493836]).[supplied by OMIM, Apr 2010]
UniProt Code:	O95907
NCBI GenInfo Identifier:	17433295
NCBI Gene ID:	23539
NCBI Accession:	O95907.1
UniProt Secondary Accession:	O95907,Q9UBE2,
UniProt Related Accession:	O95907
Molecular Weight:	52,319 Da
NCBI Full Name:	Monocarboxylate transporter 3
NCBI Synonym Full Names:	solute carrier family 16 member 8
NCBI Official Symbol:	SLC16A8
NCBI Official Synonym Symbols:	MCT3; REMP
NCBI Protein Information:	monocarboxylate transporter 3
UniProt Protein Name:	Monocarboxylate transporter 3
UniProt Synonym Protein Names:	Solute carrier family 16 member 8
Protein Family:	Monocarboxylate transporter
UniProt Gene Name:	SLC16A8
UniProt Entry Name:	MOT3_HUMAN

ELISA Kits

Human SLC16A8 ELISA Kit

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)