The SLC16A7 Polyclonal Antibody (CAB3015) is a valuable tool for researchers studying SLC16A7, a member of the monocarboxylate transporter (MCT) family that plays a crucial role in cell metabolism. This polyclonal antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to the SLC16A7 protein, allowing for accurate detection and analysis in a variety of cell types.SLC16A7 is involved in transporting monocarboxylates such as lactate, pyruvate, and ketone bodies across cell membranes, making it essential for metabolic processes and energy production.
Dysregulation of SLC16A7 has been linked to various diseases, including cancer and metabolic disorders, highlighting its importance as a potential therapeutic target.By studying the function and regulation of SLC16A7 using this polyclonal antibody, researchers can gain valuable insights into cellular metabolism and potentially identify new strategies for treating metabolic-related diseases. Its versatility and specificity make it an ideal tool for investigations in metabolism, oncology, and other fields related to cellular energetics.
Product Name:
SLC16A7 Rabbit Polyclonal Antibody
SKU:
CAB3015
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 379-478 of human SLC16A7 (NP_001257551.1).
This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
9194
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SLC16A7 Rabbit pAb (CAB3015) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
