The SLC16A7 Polyclonal Antibody (CAB12386) is a valuable tool for researchers studying SLC16A7, a member of the SLC16 gene family involved in the transport of small molecules across cell membranes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the SLC16A7 protein, this antibody enables precise detection and analysis in various cell types, making it an excellent choice for studies in areas such as metabolism, cancer biology, and drug delivery mechanisms.SLC16A7, also known as monocarboxylate transporter 2 (MCT2), plays a crucial role in the transportation of monocarboxylates such as lactate, pyruvate, and ketone bodies across cell membranes.
Dysregulation of SLC16A7 has been implicated in various diseases, including cancer, metabolic disorders, and neurological conditions. Understanding the function and regulation of SLC16A7 is essential for developing targeted therapies and strategies for managing these diseases. The SLC16A7 Polyclonal Antibody provides researchers with a reliable tool to investigate the role of SLC16A7 in health and disease, contributing to advancements in biomedical research and drug development.
Product Name:
SLC16A7 Rabbit Polyclonal Antibody
SKU:
CAB12386
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 379-478 of human SLC16A7 (NP_001257551.1).
This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
9194
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using (CAB12386) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
