The SLC16A1 Polyclonal Antibody (CAB3013) is a valuable tool for researchers studying SLC16A1, a cell membrane transporter involved in the transport of monocarboxylates such as lactate and pyruvate. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.SLC16A1, also known as the monocarboxylate transporter 1 (MCT1), is essential for a variety of cellular processes including energy metabolism, pH regulation, and lactate shuttling. Dysregulation of SLC16A1 has been implicated in various diseases such as cancer, metabolic disorders, and neurological conditions.
Understanding the function of SLC16A1 can lead to insights into disease mechanisms and potential therapeutic targets.By using the SLC16A1 Polyclonal Antibody, researchers can detect and analyze the expression of SLC16A1 in different cell types and tissues, aiding in the investigation of its role in health and disease. This antibody is a valuable tool for studies in metabolism, oncology, and neuroscience, providing crucial insight into the cellular mechanisms governed by SLC16A1.
Product Name:
MCT1/SLC16A1 Rabbit Polyclonal Antibody
SKU:
CAB3013
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 190-245 of human MCT1 (NP_003042.3).
The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6566
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from T-47D cells, using MCT1/SLC16A1 Rabbit pAb (CAB3013) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
