The SLC15A1 Polyclonal Antibody (CAB10246) is a valuable tool for researchers studying SLC15A1, a key transporter protein involved in the uptake of small peptides and bacterial peptides in the body. This antibody, generated in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding to the SLC15A1 protein, this antibody enables researchers to detect and analyze SLC15A1 in different cell types, making it ideal for studies in fields such as pharmacology, microbiology, and gastrointestinal research.
SLC15A1, also known as PEPT1, plays a crucial role in the absorption of dietary peptides and peptide-like drugs in the small intestine, contributing to nutrient uptake and drug bioavailability. Targeting SLC15A1 has implications for drug delivery and therapeutic strategies, particularly in the treatment of gastrointestinal disorders and metabolic diseases. Understanding the function of SLC15A1 is essential for developing interventions that optimize peptide absorption and improve the efficacy of peptide-based therapies.
Product Name:
SLC15A1 Rabbit Polyclonal Antibody
SKU:
CAB10246
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 600-700 of human SLC15A1 (NP_005064.1).
Sequence:
VTGL EFSY SQAP SNMK SVLQ AGWL LTVA VGNI IVLI VAGA GQFS KQWA EYIL FAAL LLVV CVIF AIMA RFYT YINP AEIE AQFD EDEK KNRL EKSN PYFM S
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
PEPT1; HPECT1; HPEPT1; SLC15A1
Positive Sample:
Mouse lung,Rat testis
Conjugate:
Unconjugated
Cellular Localization:
Membrane, Multi-pass membrane protein.
Calculated MW:
79kDa
Observed MW:
78kDa
This gene encodes an intestinal hydrogen peptide cotransporter that is a member of the solute carrier family 15. The encoded protein is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and tripeptides from the lumen into the enterocytes. This protein plays an important role in the uptake and digestion of dietary proteins. This protein also facilitates the absorption of numerous peptidomimetic drugs.
Purification Method:
Affinity purification
Gene ID:
6564
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SLC15A1 antibody (CAB10246) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
