The SLC14A2 Polyclonal Antibody (CAB13208) is a valuable tool for researchers studying SLC14A2, a critical transporter protein involved in the regulation of urea concentration in the kidney and other tissues. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the SLC14A2 protein, this antibody enables precise detection and analysis of SLC14A2 in a variety of cell types, making it an essential reagent for studies in nephrology, physiology, and related fields.SLC14A2, also known as urea transporter B, plays a crucial role in maintaining water and ion balance in the body by facilitating urea transport across cell membranes.
Dysregulation of SLC14A2 function has been linked to various kidney disorders and diseases affecting fluid homeostasis. Therefore, investigating the expression and activity of SLC14A2 is essential for understanding renal physiology and identifying potential therapeutic targets for conditions related to urea handling.In summary, the SLC14A2 Polyclonal Antibody (CAB13208) offers researchers a reliable tool for studying the function and regulation of SLC14A2 in health and disease. Its high specificity and sensitivity make it ideal for investigating the role of SLC14A2 in kidney function, fluid balance, and related physiological processes.
Product Name:
SLC14A2 Rabbit Polyclonal Antibody
SKU:
CAB13208
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 420-580 of human SLC14A2 (NP_009094.3).
The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8170
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC14A2 Rabbit pAb (CAB13208) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
