The SLC13A3 Polyclonal Antibody (CAB15183) is a valuable tool for researchers studying the SLC13A3 protein, a sodium-dependent citrate transporter involved in cellular metabolism and homeostasis. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the SLC13A3 protein, this antibody allows for the detection and analysis of SLC13A3 expression in a variety of cell types, making it an ideal choice for studies related to metabolism, transport, and cellular function.
SLC13A3 plays a crucial role in citrate transport and metabolism, impacting processes such as fatty acid synthesis, glucose utilization, and energy production in cells. Dysregulation of SLC13A3 function has been associated with various metabolic disorders, making it a target of interest in research related to diabetes, obesity, and cardiovascular diseases. By studying the activity of SLC13A3, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic approaches for their management.
Product Name:
SLC13A3 Rabbit Polyclonal Antibody
SKU:
CAB15183
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 160-240 of human SLC13A3 (NP_073740.2).
Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet.
Purification Method:
Affinity purification
Gene ID:
64849
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC13A3 Rabbit pAb (CAB15183) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
