The SLAMF8 Monoclonal Antibody (PAC015872) is a cutting-edge tool for researchers studying SLAMF8, a cell surface receptor with implications in immune regulation and inflammation. This antibody, produced through innovative technology, exhibits high specificity towards human SLAMF8 and is validated for use in various immunological assays, including flow cytometry and immunofluorescence.SLAMF8, also known as CD353, is a critical regulator of immune responses, including T cell activation and cytokine production. Its role in immune cell signaling makes it a promising target for investigations into autoimmune diseases, infectious diseases, and cancer immunotherapy.
By targeting SLAMF8, researchers can gain insights into immune system modulation and develop potential therapeutic strategies for managing immune-related disorders.Overall, the SLAMF8 Monoclonal Antibody (PAC015872) provides a valuable tool for researchers interested in unraveling the complexities of immune regulation and exploring new avenues for therapeutic interventions in various disease settings. Its high specificity and versatility make it an indispensable asset for studies in immunology, oncology, and beyond.
Antibody Name:
SLAMF8 Antibody (PACO15872)
Antibody SKU:
PACO15872
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human
Immunogen:
Fusion protein of human SLAMF8
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15872(SLAMF8 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15872(SLAMF8 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes.
Synonyms:
SLAM family member 8p
UniProt Protein Function:
SLAMF8: May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 1q23.2Cellular Component: integral to membraneMolecular Function: receptor activityBiological Process: regulation of NAD(P)H oxidase activity; regulation of kinase activity; defense response to bacterium
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes. [provided by RefSeq, Jul 2008]
