The SLAMF1 Polyclonal Antibody (CAB2044) is a vital tool for researchers studying SLAMF1, also known as signaling lymphocytic activation molecule family member 1. This cell surface receptor is involved in immune cell activation and regulation, making it a key player in immune responses.Raised in rabbits, this antibody is highly specific for human samples and has been validated for use in Western blot applications. By binding to the SLAMF1 protein, researchers can easily detect and analyze its expression in various cell types, providing valuable insights into immunology and disease mechanisms.
SLAMF1 is known for its role in T cell activation, making it a promising target for studies in immunology, infectious diseases, and autoimmune disorders. Understanding its function and regulation can lead to the development of new therapeutic strategies for modulating immune responses in conditions such as cancer, inflammatory diseases, and autoimmune disorders.Overall, the SLAMF1 Polyclonal Antibody (CAB2044) offers researchers a powerful tool for unraveling the complexities of immune regulation and signaling pathways, ultimately advancing our understanding of health and disease.
Product Name:
SLAMF1 Rabbit Polyclonal Antibody
SKU:
CAB2044
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-237 of human CD150/SLAM (NP_003028.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
37kDa
Observed MW:
37kDa/65kDa
Enables SH2 domain binding activity and identical protein binding activity. Involved in several processes, including negative regulation of CD40 signaling pathway; negative regulation of cytokine production; and positive regulation of MAPK cascade. Located in extracellular exosome.
Purification Method:
Affinity purification
Gene ID:
6504
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CD150/SLAM antibody (CAB2044) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
