SKP1 Rabbit Monoclonal Antibody (CAB9021)
- SKU:
- CAB9021
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | SKP1 Rabbit Monoclonal Antibody |
SKU: | CAB9021 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 64-163 of human SKP1 (P63208). |
Sequence: | HHKD DPPP PEDD ENKE KRTD DIPV WDQE FLKV DQGT LFEL ILAA NYLD IKGL LDVT CKTV ANMI KGKT PEEI RKTF NIKN DFTE EEEA QVRK ENQW CEEK |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | OCP2; p19A; EMC19; SKP1A; OCP-II; TCEB1L; SKP1 |
Positive Sample: | HeLa,PC-12,NIH/3T3 |
Conjugate: | Unconjugated |
Cellular Localization: | centrosome, cytoplasm, cytosol, nucleoplasm, nucleus |
Calculated MW: | 19kDa |
Observed MW: | 20kDa |
This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.
Purification Method: | Affinity purification |
Gene ID: | 6500 |
Clone Number: | ARC1384 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |