SKIV2L2 Rabbit Polyclonal Antibody (CAB5576)
- SKU:
- CAB5576
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | SKIV2L2 Rabbit Polyclonal Antibody |
SKU: | CAB5576 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-304 of human SKIV2L2 (NP_056175.3). |
Sequence: | MADA FGDE LFSV FEGD STTA AGTK KDKE KDKG KWKG PPGS ADKA GKRF DGKL QSES TNNG KNKR DVDF EGTD EPIF GKKP RIEE SITE DLSL ADLM PRVK VQSV ETVE GCTH EVAL PAEE DYLP LKPR VGKA AKEY PFIL DAFQ REAI QCVD NNQS VLVS AHTS AGKT VCAE YAIA LALR EKQR VIFT SPIK ALSN QKYR EMYE EFQD VGLM TGDV TINP TASC LVMT TEIL RSML YRGS EVMR EVAW VIFD EIHY MRDS ERGV VWEE TIIL LPDN VHYV FLSA TIPN ARQF AEWI CHLH KQPC |
Tested Applications: | WB IHC-P IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | Dob1; Mtr4; SKIV2L2; fSAP118; KIAA0052 |
Positive Sample: | HeLa,22RV1,293T,U-87MG,Mouse testis,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, nucleolus, nucleoplasm. |
Calculated MW: | 118kDa |
Observed MW: | 123kDa |
Enables ATP binding activity and RNA helicase activity. Involved in RNA catabolic process; cellular response to DNA damage stimulus; and maturation of 5.8S rRNA. Located in nucleoplasm. Part of TRAMP complex and catalytic step 2 spliceosome. Colocalizes with nuclear exosome (RNase complex). Biomarker of amyotrophic lateral sclerosis.
Purification Method: | Affinity purification |
Gene ID: | 23517 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |