The Ski Polyclonal Antibody (CAB2879) is a valuable tool for researchers studying the Ski protein, a transcriptional regulator involved in cell proliferation, differentiation, and transformation. This antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot and immunohistochemistry applications.The Ski protein is known for its role in modulating signaling pathways that regulate cell growth and survival. Dysregulation of Ski expression has been linked to cancer development, making it a promising target for cancer research and drug development. By detecting and analyzing Ski protein levels in various cell types, researchers can gain insights into its function and potential therapeutic implications in cancer treatment.
Furthermore, the Ski Polyclonal Antibody is a valuable tool for investigating the molecular mechanisms underlying cell differentiation, tissue regeneration, and developmental processes. Its specificity and sensitivity make it suitable for a wide range of research applications in cell biology, molecular biology, and oncology. Researchers can use this antibody to explore the role of Ski protein in various physiological and pathological conditions, leading to a better understanding of its function and potential clinical applications.
Product Name:
SKI Rabbit Polyclonal Antibody
SKU:
CAB2879
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 650-728 of human SKI (NP_003027.1).
This gene encodes the nuclear protooncogene protein homolog of avian sarcoma viral (v-ski) oncogene. It functions as a repressor of TGF-beta signaling, and may play a role in neural tube development and muscle differentiation.
Purification Method:
Affinity purification
Gene ID:
6497
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse fetal muscle, using SKI antibody (CAB2879).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
