The SIX3 Polyclonal Antibody (CAB17363) is a valuable tool for researchers studying the SIX3 protein, a transcription factor involved in embryonic development and cell differentiation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various applications, including immunohistochemistry and flow cytometry.SIX3 is known for its role in regulating gene expression during early development, specifically in the formation of the eye and central nervous system. Dysregulation of SIX3 has been linked to developmental disorders and certain cancers, making it a target of interest in the fields of developmental biology and oncology.
By using the SIX3 Polyclonal Antibody, researchers can accurately detect and measure levels of SIX3 in different cell types and tissues, providing valuable insights into its functions and potential therapeutic applications. This antibody is a reliable tool for elucidating the mechanisms by which SIX3 influences cellular processes and may lead to innovative treatments for related diseases.
Product Name:
SIX3 Rabbit Polyclonal Antibody
SKU:
CAB17363
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-336 of human SIX3 (NP_005404.1).
This gene encodes a member of the sine oculis homeobox transcription factor family. The encoded protein plays a role in eye development. Mutations in this gene have been associated with holoprosencephaly type 2.
Purification Method:
Affinity purification
Gene ID:
6496
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SIX3 Rabbit pAb (CAB17363) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
