The SIX2 Polyclonal Antibody (CAB8727) is a crucial tool for researchers studying the SIX2 protein, which plays a pivotal role in kidney development and maintenance. This antibody, produced in rabbits, exhibits high specificity and reactivity towards human samples, making it a reliable choice for Western blot applications. By binding to the SIX2 protein, this antibody facilitates the visualization and analysis of SIX2 expression in various cell types, making it an indispensable resource for studies in developmental biology and kidney disease research.
SIX2 is a transcription factor that is essential for the self-renewal and differentiation of renal progenitor cells during kidney development. Dysregulation of SIX2 expression has been implicated in various kidney disorders, including congenital anomalies and renal failure. By understanding the function of SIX2, researchers can gain insights into the molecular mechanisms underlying kidney development and disease pathology, leading to the identification of potential therapeutic targets for kidney-related conditions.
Product Name:
SIX2 Rabbit Polyclonal Antibody
SKU:
CAB8727
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 120-174 of human SIX2 (NP_058628.3).
This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. The encoded protein is a transcription factor which, like other members of this gene family, may be involved in limb or eye development.
Purification Method:
Affinity purification
Gene ID:
10736
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SIX2 Rabbit pAb (CAB8727) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
