The SIX1 Polyclonal Antibody (CAB11954) is a valuable tool for researchers studying SIX1, a transcription factor known for its role in development and cancer progression. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By targeting the SIX1 protein, this antibody enables the detection and analysis of SIX1 expression in various cell types, making it ideal for investigations in developmental biology and oncology research.
SIX1 is a key regulator of embryonic development and has been implicated in various types of cancer, including breast, lung, and ovarian cancer. Its involvement in tumor initiation and progression makes it a promising target for therapeutic interventions and biomarker discovery. Studying the function of SIX1 can provide valuable insights into the mechanisms driving tumorigenesis and may lead to the development of novel cancer treatments.
Product Name:
SIX1 Rabbit Polyclonal Antibody
SKU:
CAB11954
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 130-270 of human SIX1 (NP_005973.1).
The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3).
Purification Method:
Affinity purification
Gene ID:
6495
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of C2C12, using SIX1 antibody (CAB11954) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
