The SIVA1 Polyclonal Antibody (CAB6326) is a valuable tool for researchers studying SIVA1, a protein involved in apoptosis and immune regulation. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for various research applications.SIVA1 is known to play a crucial role in regulating cell death pathways and has been implicated in cancer progression and immune system function. By targeting and binding to the SIVA1 protein, this antibody enables researchers to detect and analyze SIVA1 expression in different cell types, providing valuable insights into its role in disease pathology.
With its validated use in Western blot applications, the SIVA1 Polyclonal Antibody is a reliable choice for immunology and cancer research studies. By understanding the function and activity of SIVA1, researchers can potentially uncover new therapeutic targets for cancer treatment or immune system modulation.
Product Name:
SIVA1 Rabbit Polyclonal Antibody
SKU:
CAB6326
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human SIVA1 (NP_068355.1).
This gene encodes an E3 ubiquitin ligase that regulates cell cycle progression, cell proliferation and apoptosis. The N-terminus of this protein binds to the cytoplasmic tail of the CD27 antigen, a member of the tumor necrosis factor receptor (TNFR) superfamily. In response to UV radiation-induced DNA damage, this protein has been shown to mediate the ubiquitination of proliferating cell nuclear antigen (PCNA), an important step in translesion DNA synthesis.
Purification Method:
Affinity purification
Gene ID:
10572
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using SIVA1 Rabbit pAb (CAB6326) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
