SIRT7 Rabbit Polyclonal Antibody (CAB0979)
- SKU:
- CAB0979
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | SIRT7 Rabbit Polyclonal Antibody |
SKU: | CAB0979 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 201-400 of human SIRT7 (NP_057622.1). |
Sequence: | NREY VRVF DVTE RTAL HRHQ TGRT CHKC GTQL RDTI VHFG ERGT LGQP LNWE AATE AASR ADTI LCLG SSLK VLKK YPRL WCMT KPPS RRPK LYIV NLQW TPKD DWAA LKLH GKCD DVMR LLMA ELGL EIPA YSRW QDPI FSLA TPLR AGEE GSHS RKSL CRSR EEAP PGDR GAPL SSAP ILGG WFGR GCTK RTKR KKVT |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | SIR2L7; SIRT7 |
Positive Sample: | HT-29,293T,HepG2,Mouse liver,Mouse spleen,Mouse thymus,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, nucleolus. |
Calculated MW: | 45kDa |
Observed MW: | 45kDa |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
Purification Method: | Affinity purification |
Gene ID: | 51547 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |