The SIRT6 Polyclonal Antibody (CAB18468) is a valuable tool for researchers studying SIRT6, a key protein involved in aging and metabolic regulation. This antibody, raised in rabbits, is highly specific and sensitive for detection of SIRT6 in human samples, making it ideal for use in Western blot experiments.SIRT6 is known for its role in regulating DNA repair, glucose metabolism, and inflammation, making it a promising target for research in aging, cancer, and metabolic diseases. By using the SIRT6 Polyclonal Antibody, researchers can accurately measure SIRT6 levels in different cell types and tissues, providing valuable insights into its functions and potential therapeutic applications.
With its high reactivity and specificity, the SIRT6 Polyclonal Antibody is a reliable tool for studying the intricate mechanisms of SIRT6 and its implications in various disease contexts. Its validation for Western blot applications ensures accurate and reproducible results, making it a valuable asset for studies in molecular biology, aging, and metabolic disorders.
Product Name:
SIRT6 Rabbit Polyclonal Antibody
SKU:
CAB18468
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-355 of human SIRT6 (NP_057623.2).
This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
51548
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using SIRT6 Rabbit pAb (CAB18468) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
