SIRT6 Rabbit Polyclonal Antibody (CAB18468)
- SKU:
- CAB18468
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SIRT6 Rabbit Polyclonal Antibody |
SKU: | CAB18468 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-355 of human SIRT6 (NP_057623.2). |
Sequence: | MSVN YAAG LSPY ADKG KCGL PEIF DPPE ELER KVWE LARL VWQS SSVV FHTG AGIS TASG IPDF RGPH GVWT MEER GLAP KFDT TFES ARPT QTHM ALVQ LERV GLLR FLVS QNVD GLHV RSGF PRDK LAEL HGNM FVEE CAKC KTQY VRDT VVGT MGLK ATGR LCTV AKAR GLRA CRGE LRDT ILDW EDSL PDRD LALA DEAS RNAD LSIT LGTS LQIR PSGN LPLA TKRR GGRL VIVN LQPT KHDR HADL RIHG YVDE VMTR LMKH LGLE IPAW DGPR VLER ALPP LPRP PTPK LEPK EESP TRIN GSIP AGPK QEPC AQHN GSEP ASPK RERP TSPA PHRP PKRV KAKA VPS |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | SIR2L6; hSIRT6; SIRT6 |
Positive Sample: | Mouse brain,Rat brain |
Cellular Localization: | Nucleus, nucleoplasm. |
Calculated MW: | 39kDa |
Observed MW: | 39kDa |
This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 51548 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |