SIRT6 Rabbit Monoclonal Antibody (CAB3591)
- SKU:
- CAB3591
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SIRT6 Rabbit Monoclonal Antibody |
SKU: | CAB3591 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 256-355 of human SIRT6 (Q8N6T7). |
Sequence: | GYVD EVMT RLMK HLGL EIPA WDGP RVLE RALP PLPR PPTP KLEP KEES PTRI NGSI PAGP KQEP CAQH NGSE PASP KRER PTSP APHR PPKR VKAK AVPS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | SIR2L6; hSIRT6; SIRT6 |
Positive Sample: | HeLa,A549,MCF7 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, Endoplasmic reticulum |
Calculated MW: | 39kDa |
Observed MW: | 40kDa |
This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 51548 |
Clone Number: | ARC0808 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |