SIRT6 Rabbit Polyclonal Antibody (CAB7416)
- SKU:
- CAB7416
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SIRT6 Rabbit Polyclonal Antibody |
SKU: | CAB7416 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-294 of mouse SIRT6 (NP_001156902.1). |
Sequence: | NLQP TKHD RQAD LRIH GYVD EVMC RLMK HLGL EIPA WDGP CVLD KALP PLPR PVAL KAEP PVHL NGAV HVSY KSKP NSPI LHRP PKRV KTEA APS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | Sir2l6; mSIRT6; 2810449N18Rik; SIRT6 |
Positive Sample: | HeLa,293T,Mouse spleen,Mouse stomach,A-549,LO2,BT-474,HL-60,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, nucleoplasm. |
Calculated MW: | 39kDa |
Observed MW: | 39-45kDa |
Enables several functions, including NAD(P)+-protein-arginine ADP-ribosyltransferase activity; NAD-dependent histone deacetylase activity (H3-K9 specific); and transcription corepressor activity. Involved in several processes, including cellular protein modification process; negative regulation of nucleobase-containing compound metabolic process; and positive regulation of cell population proliferation. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; gonad; musculature; and retina. Used to study progeria. Orthologous to human SIRT6 (sirtuin 6).
Purification Method: | Affinity purification |
Gene ID: | 50721 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |