SIRT6 Polyclonal Antibody (CAB21535)
- SKU:
- CAB21535
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | SIRT6 Polyclonal Antibody |
SKU: | CAB21535 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 251-355 of human SIRT6 (NP_057623.2). |
Sequence: | DLRI HGYV DEVM TRLM KHLG LEIP AWDG PRVL ERAL PPLP RPPT PKLE PKEE SPTR INGS IPAG PKQE PCAQ HNGS EPAS PKRE RPTS PAPH RPPK RVKA KAVP S |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SIR2L6; hSIRT6; SIRT6 |
Positive Sample: | A549,HeLa,L-O2,BT-474,HL-60,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, nucleoplasm. |
Calculated MW: | 39kDa |
Observed MW: | Refer to figures |
This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 51548 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |