SIRT5 Polyclonal Antibody (CAB21827)
- SKU:
- CAB21827
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | SIRT5 Polyclonal Antibody |
SKU: | CAB21827 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 216-310 of human SIRT5 (NP_036373.1). |
Sequence: | LRPH VVWF GENL DPAI LEEV DREL AHCD LCLV VGTS SVVY PAAM FAPQ VAAR GVPV AEFN TETT PATN RFRF HFQG PCGT TLPE ALAC HENE TVS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | SIR2L5; SIRT5 |
Positive Sample: | HCT116,HepG2,SKOV3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion, Mitochondrion intermembrane space, Mitochondrion matrix, Nucleus, cytosol. |
Calculated MW: | 34kDa |
Observed MW: | 30kDa |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 23408 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |