[KO Validated] SIRT5 Rabbit Polyclonal Antibody (CAB5784)
- SKU:
- CAB5784
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] SIRT5 Rabbit Polyclonal Antibody |
SKU: | CAB5784 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 37-310 of human SIRT5 (NP_036373.1). |
Sequence: | SSSM ADFR KFFA KAKH IVII SGAG VSAE SGVP TFRG AGGY WRKW QAQD LATP LAFA HNPS RVWE FYHY RREV MGSK EPNA GHRA IAEC ETRL GKQG RRVV VITQ NIDE LHRK AGTK NLLE IHGS LFKT RCTS CGVV AENY KSPI CPAL SGKG APEP GTQD ASIP VEKL PRCE EAGC GGLL RPHV VWFG ENLD PAIL EEVD RELA HCDL CLVV GTSS VVYP AAMF APQV AARG VPVA EFNT ETTP ATNR FRFH FQGP CGTT LPEA LACH ENET VS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | SIR2L5; T5 |
Positive Sample: | HCT 116,293F,Mouse heart,Mouse liver,Rat heart,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion, Mitochondrion intermembrane space, Mitochondrion matrix, Nucleus, cytosol. |
Calculated MW: | 34kDa |
Observed MW: | 35kDa |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 23408 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |