SIRT4 Rabbit Polyclonal Antibody (CAB7585)
- SKU:
- CAB7585
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | SIRT4 Rabbit Polyclonal Antibody |
SKU: | CAB7585 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-313 of human SIRT4 (NP_036372.1). |
Sequence: | IGLF VPAS PPLD PEKV KELQ RFIT LSKR LLVM TGAG ISTE SGIP DYRS EKVG LYAR TDRR PIQH GDFV RSAP IRQR YWAR NFVG WPQF SSHQ PNPA HWAL STWE KLGK LYWL VTQN VDAL HTKA GSRR LTEL HGCM DRVL CLDC GEQT PRGV LQER FQVL NPTW SAEA HGLA PDGD VFLS EEQV RSFQ VPTC VQCG GHLK PDVV FFGD TVNP DKVD FVHK RVKE ADSL LVVG SSLQ VYSG YRFI LTAW EKKL PIAI LNIG PTRS DDLA CLKL NSRC GELL PLID P |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | SIR2L4; SIRT4 |
Positive Sample: | Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix. |
Calculated MW: | 35kDa |
Observed MW: | 32kDa |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
Purification Method: | Affinity purification |
Gene ID: | 23409 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |