The SIPA1L2 Polyclonal Antibody (PAC041766) is a vital tool for research involving SIPA1L2, a protein involved in cell signaling and cancer progression. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By selectively binding to the SIPA1L2 protein, this antibody enables accurate detection and analysis in various cell types, making it an excellent choice for studies in cancer biology and signal transduction research.SIPA1L2, also known as signal-induced proliferation-associated-like protein 2, plays a crucial role in modulating cellular signaling pathways involved in cell growth and metastasis.
Its involvement in cancer progression makes it a promising target for research into novel therapeutic strategies for cancer treatment. Understanding the function of SIPA1L2 is essential for uncovering its potential as a biomarker or therapeutic target in various types of cancer.Overall, the SIPA1L2 Polyclonal Antibody is a valuable tool for researchers aiming to unravel the complexities of SIPA1L2 protein function and its implications in cancer biology. Its high specificity and efficacy in detecting SIPA1L2 make it an indispensable asset for studies exploring the molecular mechanisms underlying cancer development and progression.
Antibody Name:
SIPA1L2 Antibody (PACO41766)
Antibody SKU:
PACO41766
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Signal-induced proliferation-associated 1-like protein 2 protein (522-778AA)
Immunohistochemistry of paraffin-embedded human liver cancer using PACO41766 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO41766 at dilution of 1:100.
Synonyms:
Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2), SIPA1L2, KIAA1389
UniProt Protein Function:
SIPA1L2: 2 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs; GAPs, RasChromosomal Location of Human Ortholog: 1q42.2Molecular Function: GTPase activator activity; protein bindingBiological Process: positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the signal-induced proliferation-associated 1 like family. Members of this family contain a GTPase activating domain, a PDZ domain and a C-terminal coiled-coil domain with a leucine zipper. A similar protein in rat acts as a GTPases for the small GTPase Rap. [provided by RefSeq, Sep 2015]
