The SIPA1L1 Polyclonal Antibody (CAB18445) is a valuable tool for research involving SIPA1L1, a protein involved in cell signaling pathways and cancer progression. This rabbit-derived antibody is highly specific to SIPA1L1 in human samples and has been validated for use in Western blot applications. By binding to SIPA1L1, this antibody enables precise detection and analysis of the protein in various cell types, making it ideal for studies in cancer biology and signal transduction research.SIPA1L1 is a scaffold protein that plays a crucial role in regulating cell proliferation, migration, and invasion, making it a potential target for cancer therapy.
Understanding the function of SIPA1L1 can provide valuable insights into the mechanisms of cancer development and progression. Research into SIPA1L1 may lead to the development of novel targeted therapies for cancer treatment, making this antibody an essential tool for scientists investigating cancer biology and therapeutic strategies.
Product Name:
SIPA1L1 Rabbit Polyclonal Antibody
SKU:
CAB18445
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1480-1700 of human SIPA1L1 (NP_056371.1).
actin cytoskeleton, cytoplasm, dendritic spine, plasma membrane, postsynaptic density
Calculated MW:
200kDa
Observed MW:
180kDa
Predicted to enable GTPase activator activity; actin filament binding activity; and protein kinase binding activity. Predicted to be involved in several processes, including actin cytoskeleton organization; activation of GTPase activity; and regulation of postsynapse organization. Located in actin cytoskeleton and plasma membrane.
Purification Method:
Affinity purification
Gene ID:
26037
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain, using SIPA1L1 Rabbit pAb (CAB18445) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
