SIPA1 Rabbit Polyclonal Antibody (CAB12253)
- SKU:
- CAB12253
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SIPA1 Rabbit Polyclonal Antibody |
SKU: | CAB12253 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 763-1042 of human SIPA1 (NP_694985.29). |
Sequence: | ESGR PRRS FSEL YTLS LQEP SRRG APDP VQDE VQGV TLLP TTKQ LLHL CLQD GGSP PGPG DLAE ERTE FLHS QNSL SPRS SLSD EAPV LPNT TPDL LLAT TAKP SVPS ADSE TPLT QDRP GSPS GSED KGNP APEL RASF LPRT LSLR NSIS RIMS EAGS GTLE DEWQ AISE IAST CNTI LESL SREG QPIP ESGD PKGT PKSD AEPE PGNL SEKV SHLE SMLR KLQE DLQK EKAD RAAL EEEV RSLR HNNR RLQA ESES AATR LLLA SKQL GSPT ADLA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SPA1; SIPA1 |
Positive Sample: | Raji,K-562,HeLa,LO2,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endomembrane system, Nucleus, Peripheral membrane protein, perinuclear region. |
Calculated MW: | 112kDa |
Observed MW: | 130kDa |
The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.
Purification Method: | Affinity purification |
Gene ID: | 6494 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |