The SIN3A Polyclonal Antibody (CAB1577) is a versatile tool for researchers studying the SIN3A protein, a key component of the SIN3 transcriptional regulator complex involved in gene regulation and chromatin remodeling. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications.SIN3A is known to play a crucial role in various cellular processes, including cell cycle regulation, DNA repair, and apoptosis. Dysregulation of SIN3A has been implicated in diseases such as cancer and neurological disorders, making it an important target for further investigation.
The SIN3A Polyclonal Antibody enables the detection and analysis of SIN3A protein expression in different cell types, providing valuable insights for studies in molecular biology and disease research.By understanding the functions and regulation of SIN3A, researchers can uncover new therapeutic targets and develop novel treatments for diseases associated with SIN3A dysregulation. The SIN3A Polyclonal Antibody offers a reliable tool for investigating the role of SIN3A in various biological processes, contributing to advancements in biomedical research.
Product Name:
SIN3A Rabbit Polyclonal Antibody
SKU:
CAB1577
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-120 of human Sin3A (NP_056292.1).
The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex.
Purification Method:
Affinity purification
Gene ID:
25942
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using Sin3A Rabbit pAb (CAB1577) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
