SIM2 Rabbit Polyclonal Antibody (CAB15098)
- SKU:
- CAB15098
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | SIM2 Rabbit Polyclonal Antibody |
SKU: | CAB15098 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 342-525 of human SIM2 (NP_005060.1?). |
Sequence: | LSLE QVST AKSQ DSWR TALS TSQE TRKL VKPK NTKM KTKL RTNP YPPQ QYSS FQMD KLEC GQLG NWRA SPPA SAAA PPEL QPHS ESSD LLYT PSYS LPFS YHYG HFPL DSHV FSSK KPML PAKF GQPQ GSPC EVAR FFLS TLPA SGEC QWHY ANPL VPSS SSPA KNPP EPPA NTAR HSLV PSYE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SIM; bHLHe15; HMC13F06; HMC29C01; SIM2 |
Positive Sample: | HepG2,PC-3,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 73kDa |
Observed MW: | 73kDa |
This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 6493 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |