The Sik3 Polyclonal Antibody (CAB8019) is a valuable tool for researchers studying the Sik3 protein, a member of the AMP-activated protein kinase (AMPK) family that plays a crucial role in regulating energy metabolism and cell growth. Raised in rabbits, this antibody is highly specific for human samples and is validated for use in Western blot applications.Sik3 is involved in various cellular processes, including glucose metabolism, adipocyte differentiation, and insulin signaling. Dysregulation of Sik3 has been linked to metabolic disorders, cancer, and other diseases, making it a promising target for therapeutic interventions.
By binding to Sik3, this antibody enables researchers to detect and analyze the protein in different cell types, facilitating studies in metabolic biology, oncology, and drug development.Overall, the Sik3 Polyclonal Antibody is an essential tool for investigating the role of Sik3 in cellular physiology and disease pathogenesis, providing valuable insights into potential therapeutic strategies for metabolic and oncologic conditions.
Product Name:
SIK3 Polyclonal Antibody
SKU:
CAB8019
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-310 of human SIK3 (NP_079440.3).
Enables ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in positive regulation of TORC1 signaling; positive regulation of TORC2 signaling; and protein phosphorylation. Located in nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
23387
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of 293F, using SIK3 Rabbit pAb (CAB8019) at 1:6000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
