SIGMAR1 Rabbit Polyclonal Antibody (CAB5479)
- SKU:
- CAB5479
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SIGMAR1 Rabbit Polyclonal Antibody |
SKU: | CAB5479 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 114-223 of human SIGMAR1 (NP_005857.1). |
Sequence: | RGHS GRYW AEIS DTII SGTF HQWR EGTT KSEV FYPG ETVV HGPG EATA VEWG PNTW MVEY GRGV IPST LAFA LADT VFST QDFL TLFY TLRS YARG LRLE LTTY LFGQ DP |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:100 - 1:200 |
Synonyms: | SRBP; ALS16; DSMA2; OPRS1; SR-BP; SIG-1R; SR-BP1; sigma1R; hSigmaR1; SIGMAR1 |
Positive Sample: | HL-60,293T,SKOV3,Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cell projection, Endoplasmic reticulum membrane, Lipid droplet, Nucleus inner membrane, Nucleus outer membrane, growth cone. |
Calculated MW: | 25kDa |
Observed MW: | 25kDa |
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 10280 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |