The Siglec9 Polyclonal Antibody (CAB4648) is an essential tool for researchers studying Siglec9, a cell surface protein involved in immune regulation. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By specifically binding to the Siglec9 protein, this antibody enables researchers to detect and analyze its expression in various cell types, making it an invaluable tool for studies in immunology and cancer research.Siglec9, a member of the sialic acid-binding Ig-like lectin (Siglec) family, plays a crucial role in immune response modulation by regulating inflammation and inhibiting immune activation. Its involvement in immune regulation highlights its potential as a therapeutic target for diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
Understanding the function of Siglec9 is essential for developing novel treatments that manipulate immune responses in the context of these diseases.Overall, the Siglec9 Polyclonal Antibody (CAB4648) offers researchers a reliable tool for investigating the role of Siglec9 in immune regulation and disease pathogenesis. Its high specificity and sensitivity make it an ideal choice for studies aiming to uncover the mechanisms underlying immune dysfunction and develop targeted therapies for various immune-related disorders.
Product Name:
SIGLEC9 Rabbit Polyclonal Antibody
SKU:
CAB4648
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 210-340 of human SIGLEC9 (NP_001185487.1).
Predicted to enable monosaccharide binding activity and sialic acid binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within negative regulation of inflammatory response and negative regulation of phagocytosis, engulfment. Predicted to be located in external side of plasma membrane. Predicted to be active in plasma membrane.
Purification Method:
Affinity purification
Gene ID:
27180
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SIGLEC9 Rabbit pAb (CAB4648) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
