The Siglec6 Polyclonal Antibody (CAB12387) is a valuable tool for researchers studying Siglec6, a member of the sialic acid-binding immunoglobulin-like lectins (Siglecs) family. This antibody is raised in rabbits and is highly specific for detecting Siglec6 in human samples. Validated for use in Western blot applications, this antibody binds to the Siglec6 protein, allowing for accurate detection and analysis in a variety of cell types.Siglec6 has been implicated in various immune processes, including regulation of immune responses and interactions with sialic acid-containing molecules. Research into Siglec6 has highlighted its potential role in modulating immune function in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
By understanding the activity of Siglec6, researchers can develop targeted therapies that aim to manipulate immune responses for therapeutic benefit.Overall, the Siglec6 Polyclonal Antibody is a valuable tool for researchers investigating the role of Siglec6 in immunology and disease pathology. Its high specificity and reactivity make it an ideal choice for studies aimed at uncovering the functions and therapeutic potential of this important immune regulator.
Product Name:
SIGLEC6 Rabbit Polyclonal Antibody
SKU:
CAB12387
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-220 of human SIGLEC6 (NP_942142.3).
Cell membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
50kDa
Observed MW:
72kDa
This gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin-like lectin) family of proteins. The encoded transmembrane receptor binds sialyl-TN glycans and leptin. Placental expression of the encoded protein is upregulated in preeclampsia.
Purification Method:
Affinity purification
Gene ID:
946
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from U-937 cells, using SIGLEC6 Rabbit pAb (CAB12387) at 1:700 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
