SIGLEC5 Rabbit Polyclonal Antibody (CAB4250)
- SKU:
- CAB4250
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SIGLEC5 Rabbit Polyclonal Antibody |
SKU: | CAB4250 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 17-434 of human SIGLEC5 (NP_003821.1). |
Sequence: | EKPV YELQ VQKS VTVQ EGLC VLVP CSFS YPWR SWYS SPPL YVYW FRDG EIPY YAEV VATN NPDR RVKP ETQG RFRL LGDV QKKN CSLS IGDA RMED TGSY FFRV ERGR DVKY SYQQ NKLN LEVT ALIE KPDI HFLE PLES GRPT RLSC SLPG SCEA GPPL TFSW TGNA LSPL DPET TRSS ELTL TPRP EDHG TNLT CQMK RQGA QVTT ERTV QLNV SYAP QTIT IFRN GIAL EILQ NTSY LPVL EGQA LRLL CDAP SNPP AHLS WFQG SPAL NATP ISNT GILE LRRV RSAE EGGF TCRA QHPL GFLQ IFLN LSVY SLPQ LLGP SCSW EAEG LHCR CSFR ARPA PSLC WRLE EKPL EGNS SQGS FKVN SSSA GPWA NSSL ILHG GLSS DLKV SCKA WNIY GSQS GSVL LLQG RSNL GT |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CD170; OBBP2; CD33L2; OB-BP2; SIGLEC-5; SIGLEC5 |
Positive Sample: | Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 61kDa |
Observed MW: | 70kDa |
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.
Purification Method: | Affinity purification |
Gene ID: | 8778 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |