The Siglec15 Polyclonal Antibody (CAB18660) is a valuable tool for researchers studying Siglec15, a cell surface protein involved in immune regulation and tumor immunity. This rabbit-derived antibody is highly specific and reacts with human samples, making it ideal for Western blot applications to detect and analyze Siglec15 expression in various cell types.Siglec15 is a member of the Siglec family of proteins, which are known to play a critical role in immune responses and inflammation regulation. Research has shown that Siglec15 is upregulated in certain types of cancer, suggesting a role in tumor immune evasion.
By targeting Siglec15 with this antibody, researchers can explore its function in cancer biology and potentially develop novel therapies for cancer treatment.Overall, the Siglec15 Polyclonal Antibody is a valuable tool for researchers investigating the role of Siglec15 in immune regulation and cancer biology. Its high specificity and reactivity make it a reliable reagent for studies in immunology and oncology.
Product Name:
SIGLEC15 Rabbit Polyclonal Antibody
SKU:
CAB18660
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-263 of human Siglec-15 (NP_998767.1).
Predicted to be involved in regulation of actin cytoskeleton organization; regulation of bone resorption; and regulation of osteoclast development. Predicted to be integral component of membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane.
Purification Method:
Affinity purification
Gene ID:
284266
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Siglec-15 Rabbit pAb (CAB18660) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
